| Cannon Expert (5) | Pierce at least 10 enemies with a single cannonball. |
| Co-op Beginner (5) | Complete any level in co-op. |
| Co-op Hippie (10) | Complete The Great Pyramid in co-op with blood option set to hippie. |
| Game Master (20) | Complete the game. |
| I am Invincible (10) | Complete the game in single player without firing a single bullet or shell. |
| Look, It's a Secret (30) | Find at least 50 secrets in single player. |
| Metropolis King (20) | Complete Metropolis level in single player on serious difficulty without loading. |
| Perfect Kill (10) | Kill all enemies in Karnak in single player. |
| Serious Beginner (10) | Complete any level in single player. |
| Serious Co-op (35) | Complete a co-op game on serious difficulty and extra enemy strength on 400%. |
| Serious Run (15) | Complete the game in single player by beating estimated time on each level. |
| Serious Sam (30) | Complete the game in single player on serious difficulty. |
