| A Fistful of Revenge (50) | Ride "Burrito" the Dog into the sunset. |
| A Long Fall to Hell (20) | Find a way to kill an undead puppet. |
| Awesomeness Detected (20) | Do something really awesome. |
| Back Seat Commentator (5) | Listen to a different kind of narrator while you play. |
| Big Spender (25) | Purchase everything in the bonus store. |
| Death Rides a Steamboat (20) | Commit mass destruction with a paddleboat. |
| For A Few Gallons More (30) | Take down Big Oil. |
| Gold Medallist (20) | Reach a Gold Medal score on a single act. |
| Great Balls of Fire (20) | Survive an epic battle against a kite. |
| Hot Lead Pusher (20) | Get a crazy high kill streak. |
| How The East Was Won (30) | Possess a lush, full beard. |
| Hundred Thousand Dollar Baby (20) | Spend a whole chunk of money in the bonus store. |
| Legend of the 8000 Samurai (20) | Find the Great Wall of China in an unexpected place. |
| Living Large in the Saddle (10) | Hoard all the tacos and hearts in an act. |
| Lonely Are The Dead (30) | Face Death and live to tell the tale. |
| Lucky Prize Winner (15) | Find an achievement hidden in a piece of concept art. |
| Money is the Best Medicine (20) | Earn cash, not health, for every heart in an act. |
| My Horse, A Gun, Your Lumberjack (20) | Find a place to saw some logs. |
| No Country for Old Barons (20) | Carjack a stagecoach. |
| No Insurance (15) | Don't scratch the paint while piloting a paddleboat. |
| Once Upon a Time in the West (20) | End an artist's career. |
| Perfect Performance (25) | Win gold medals in all acts of a single play. |
| Perfectionist (30) | Win a gold medal in every act of every play. |
| Pistol for a Hundred Skeletons (20) | Kill 18,675,309,000 Skeletons. |
| Requiem for a Gunstringer (20) | Walk amongst the dead. |
| Russian Chicken (10) | In a shootout, play chicken with a bullet before shooting it. |
| Sellout (10) | Buy an achievement from the bonus store. |
| Seven Shooter (5) | Defy laws of physics by shooting more than six enemies without reloading. |
| Stranger in New Orleans (20) | Take Andrew Jackson to the Madam's district. |
| Strings of Steel (50) | Beat every play in one session. On Hardcore Mode. Also, never die. |
| The Backwards Bandit (20) | Complete a level with "Lefty Mode" enabled. |
| The Bandit Sheriff (20) | Close your bank account. |
| The Big Easy Reckoning (30) | Get close and personal with the Madam. |
| The Brute and the Beast (20) | See things that you will never be able to unsee. |
| The Canyon Runs Red (20) | Fall thousands of feet without dying. |
| The Great Wall of Vengeance (20) | Ride a rocket over a battlefield. |
| The Gunstringer Rides Again (15) | Destroy the advertising plan of a small business. |
| The Hidden Fortress (20) | Crash into someone's house uninvited. |
| The Last Undead Boy Scout (20) | Collect a gold medal, hardcore award, and 2P award in a single act. |
| The Lone Star (20) | Finish an act while playing on Hardcore Mode. |
| The Red Baron (25) | Kill 100 enemies while strapped to a rocket in "The Great Wall of Vengeance". |
| Tin Marksman (5) | Shoot all the cans in the Prologue. |
| Took a Bullet for the Team (10) | Take down the developers. |
| Turbo Deflation (10) | Deflate the first boss in under 30 seconds. |
| Two Hearts to Live (20) | Complete all acts in a play without ever dropping to one heart. |
| Undead and Untouchable (20) | Reach the end of "Requiem for a Gunstringer" without losing a single heart. |
| Undead or Alive (20) | Remember the time you scorned a woman. |
| What's Next? (5) | Visit the Download Content screen to see what new content is available. |
| Why Would You Even Do This? (25) | Complete an act with every single modifier enabled. |
| With a Little Help from a Friend (15) | Complete an act with a friend. |
