| . . . And Thanks For Stopping By (25) | Dishonorably discharge Major Talbot. |
| A Leader In His Field (10) | Enlist Samuel Sterns in the search for a cure to Banner’s condition. |
| Abominable! (50) | Defeat the Abomination. |
| Alia Iacta Est (25) | Protect General Ross's team while they attack the Enclave base. |
| All That Glitters . . . (50) | Win a gold medal in every mini-game. |
| Anger Management (40) | Find all the Fury Canisters hidden in New York City. |
| Apprentice Of Disaster (25) | Destroy a building in each New York City neighborhood. |
| Around The World In 80 Steps (5) | Cross the tops of the flagpoles outside the U.N. Building. |
| Better, Stronger, Faster! (15) | Get a power boost from Samuel Sterns. |
| Brawn Beats Brains (25) | Shut down the Enclave's psych-ops branch. |
| Ceres Finale (25) | Shut down the Enclave's biotech group. |
| Don't Make Me Angry (5) | Defeat 50 enemies using Rage powers. |
| Enemy Of The Empire State (50) | Find every landmark souvenir in New York City. |
| Eww . . . Gross! (10) | Test the cure developed by Samuel Sterns. |
| Fairweather Friends (25) | Shut down the Enclave's weather manipulation division. |
| Fear Of Falling (5) | Complete "We’re Not Giving Up – Part 2" without touching the ground. |
| Home Run (5) | Knock an enemy a distance of at least 436 feet. |
| Hulk Is Strongest One There Is! (50) | Gain access to all the upgrades. |
| Hulk SMASH!!! (15) | Defeat at least 1 enemy with each class of attack. |
| Let's Do Lunch! (10) | Crush 10 enemies by throwing either a taco, an ice cream cone or a doughnut. |
| Love Hurts (20) | Ignite an old flame . . . |
| Mad Dash (10) | Sprint a total distance of at least 26.2 miles (138,435ft). |
| Master Of Disaster (35) | Destroy every building in a New York City neighborhood. |
| Most Illogical (25) | Shut down the Enclave's mechanical design corps. |
| Now Playing (10) | Score 6,132,008 points. |
| Over The Edge (10) | Defeat 5 enemies by knocking them off a high building. |
| Para-Gone! (50) | Wipe out the Enclave's four sectors. |
| Patron Of The Arts (15) | View every piece of concept art at least once. |
| Pickin' Up The Pieces (20) | Smash 10,000 things. |
| PPO'd (40) | Find all the Gamma Canisters hidden in New York City. |
| Pure As New York Snow (10) | Clean up the contamination from the streets of New York. |
| Shell-Head (10) | With a friend like this . . . |
| Sightseeing (5) | Climb to the top of the five tallest buildings in New York City. |
| Smash-ifist (10) | Win a story mission without defeating any enemies. |
| Stay Classy . . . (20) | Expose Major Talbot on television. |
| Struck Out (5) | Complete "The Problem is the Hulk - Part 3" without being hit by a lightning blast. |
| Surprise! (10) | Encounter General Ross’s Spec Ops team for the first time. |
| Terrifying Tourist (10) | Find every Subway Station in New York. |
| That'll Leave A Mark (10) | Stick 25 auto-wrecks to buildings. |
| The Enemy Of My Enemy (25) | Defeat Enclave’s F-POD...with a little help. |
| The Eyes Have It (10) | Destroy an Enclave Kyklops for the first time. |
| There Is No U In Team! (10) | Trick a U-Foe into taking down one of his or her teammates. |
| Thrill-ionaire (25) | Score 1,000,000 points while Strike Teams are active. |
| Two Heads Aren’t Better Than One (15) | Defeat the Bi-Beast. |
| Unleash the Fury! (5) | Get the Enclave off your back. |
| Veni, Vidi, Vici (50) | Defeat every type of enemy at least once. |
| What Goes Up . . . (20) | Crash and destroy the Enclave’s Lightning Satellite. |
| Where Is My KA-BOOM? (10) | Save New York from the Enclave Chemical Bomb. |
| World War Hulk (25) | Survive for longer than 60 seconds at Threat Level 9. |
| You Break It, You Buy It (10) | Smash as much as possible in one trip to Brazil. |
