| All in the reflexes (10) | Kill 3 enemies at once in a single eQM |
| Between Old Friends (25) | Kill The Immortal with Cross on The Killer Difficulty |
| Boom! (5) | Kill one explosive rat |
| Bullet Curving Expert (25) | Kill 100 enemies using Curved Bullets |
| Bullet Curving Trainee (5) | Kill 10 enemies using Curved Bullets |
| Butcher would be proud (50) | Complete the game in "Close Combat Mode", any difficulty |
| Catch me if you can (50) | 1st position in "Time Attack" Ranking |
| Collector Nerd (10) | Find 10 reward items |
| Completed Act 1 - Assassin (20) | Complete Act 1 - Assassin Difficulty |
| Completed Act 1 - Easy (10) | Complete Act 1 - Easiest Difficulty |
| Completed Act 1 - The Killer (30) | Complete Act 1 - The Killer Difficulty |
| Completed Act 2 - Assassin (20) | Complete Act 2 - Assassin Difficulty |
| Completed Act 2 - Easy (10) | Complete Act 2 - Easiest Difficulty |
| Completed Act 2 - The Killer (30) | Complete Act 2 - The Killer Difficulty |
| Completed Act 3 - Assassin (20) | Complete Act 3 - Assassin Difficulty |
| Completed Act 3 - Easy (10) | Complete Act 3 - Easiest Difficulty |
| Completed Act 3 - The Killer (30) | Complete Act 3 - The Killer Difficulty |
| Completed Act 4 - Assassin (20) | Complete Act 4 - Assassin Difficulty |
| Completed Act 4 - Easy (10) | Complete Act 4 - Easiest Difficulty |
| Completed Act 4 - The Killer (30) | Complete Act 4 - The Killer Difficulty |
| Completed Act 5 - Assassin (20) | Complete Act 5 - Assassin Difficulty |
| Completed Act 5 - Easy (10) | Complete Act 5 - Easiest Difficulty |
| Completed Act 5 - The Killer (30) | Complete Act 5 - The Killer Difficulty |
| Completed Act 6 - Assassin (20) | Complete Act 6 - Assassin Difficulty |
| Completed Act 6 - Easy (10) | Complete Act 6 - Easiest Difficulty |
| Completed Act 6 - The Killer (30) | Complete Act 6 - The Killer Difficulty |
| Completed Act 7 - Assassin (20) | Complete Act 7 - Assassin Difficulty |
| Completed Act 7 - Easy (10) | Complete Act 7 - Easiest Difficulty |
| Completed Act 7 - The Killer (30) | Complete Act 7 - The Killer Difficulty |
| Completed Act 8 - Assassin (20) | Complete Act 8 - Assassin Difficulty |
| Completed Act 8 - Easy (10) | Complete Act 8 - Easiest Difficulty |
| Completed Act 8 - The Killer (30) | Complete Act 8 - The Killer Difficulty |
| Compulsive Hoarder (30) | Find all reward items |
| Dr. Lobotomy (50) | Complete the game in "Headshot Mode", any difficulty |
| Fully trained assassin (30) | Complete Act 9 - Assassin Difficulty |
| Glad I wasn't there (10) | Kill 3 enemies at once with a single Explosive Bullet |
| Half the man Barry is (5) | Kill Kathy, ex-girlfriend |
| Heart Breaker (25) | Kill Aran~a with Wesley without mask on The Killer Difficulty |
| I am in control (5) | Complete the 1st Tutorial |
| I have it in my blood (5) | Complete the 2nd Tutorial |
| Kill One, Save a Thousand Donuts (5) | Kill Janice, ex-boss |
| No more anxiety attacks (5) | Complete the 3rd Tutorial |
| Pest Exterminator (20) | Kill all explosive rats |
| Punishing Subordinates (25) | Kill The Russian with The Immortal in close combat and The Killer Difficulty |
| Ready to play with the big boys (15) | Complete Act 9 - Easiest Difficulty |
| Shrapnel Storm Expert (25) | Kill 80 enemies using Bullet Explosions |
| Shrapnel Storm Trainee (5) | Kill 10 enemies using Bullet Explosions |
| The Killer (50) | Complete Act 9 - The Killer Difficulty |
| Two is always better than one (10) | Kill 2 enemies at once with a single Curved Bullet |
| Up close and personal (20) | Kill 15 enemies in close combat |
